J Biomed 2017; 2:124-133. doi:10.7150/jbm.18967


A scientometric review of glycocalyx research (2007—2016)

Yu Zhang1, Ye Zeng2✉

1. Sichuan University Library, Sichuan University, Chengdu 610041, China;
2. Institute of Biomedical Engineering, School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.


The glycocalyx is a carbohydrate-rich layer that lines the luminal side of the epithelial cells in mammals. This structure is not just a barrier for vascular permeability but also contributes to various functions including the signal sensing and transmission of heamodynamic forces to the endothelium, the regulation of cell proliferation, differential and apoptosis. In this review, we conducted a scientometric analysis to summarize the panoramic network of the international research in the field of glycocalyx during the recent decades. With the help of Citespace software, a visual bibliometric analysis of references regarding glycocalyx research during years 2007-2016 was made. Finally, different visual maps were generated and a group of valuable conclusions were extracted from these maps, including prominent authors, critical articles, hot research topics, emerging trends and research front in the field of glycocalyx research, which is helpful for the comprehensive understanding of the advances in recent glycocalyx researches.

Keywords: scientometric, glycocalyx, Citespace.

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How to cite this article:
Zhang Y, Zeng Y. A scientometric review of glycocalyx research (2007—2016). J Biomed 2017; 2:124-133. doi:10.7150/jbm.18967. Available from http://www.jbiomed.com/v02p0124.htm